Genome editing with DNA-dependent polymerases
Technology tamfitronics
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Gene editing
Nature Biotechnology (2024)Cite this article
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Two CRISPR tools harness DNA-dependent polymerases for genome editing — and may overcome some limitations of prime editors.
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Competing interests
A.C.K. is a member of the scientific advisory board of Pairwise Plants, is an equity holder in Pairwise Plants and Beam Therapeutics, and receives royalties from Pairwise Plants, Beam Therapeutics and Editas Medicine via patents licensed from Harvard University. A.C.K.’s interests have been reviewed and approved by the University of California, San Diego in accordance with its conflict of interest policies. Q.T.C. declares no competing financial interests.
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Cowan, Q.T., Komor, A.C. Genome editing with DNA-dependent polymerases. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02372-3
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DOI: https://doi.org/10.1038/s41587-024-02372-3