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Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues

Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues

Technology tamfitronics Main Chromatin organization plays a crucial role in both embryonic development1,2 and the progression of various diseases3,4. During development, the chromatin structure influences which genes are turned on or off by the distal regulatory elements5,6,7,8. Abnormal chromatin organization can lead to aberrant gene expression or silencing, contributing to cancer development and metastasis4. Indeed, […]

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