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Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation

Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation

Technology tamfitronics Data availability WES and RNA-seq data from the training HCT, DFCI-MRD and HP-MRD cohorts is available through the dbGaP portal (accession phs003394.v1.p1). The original mass spectra, PSMs and protein sequence databases used for searches have been deposited in the public proteomics repository MassIVE (https://massive.ucsd.edu) and are accessible at ftp://massive.ucsd.edu/v08/MSV000095025/. Original mass spectrometry data […]

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Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology

Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology

Technology tamfitronics Chandrashekhar Madasu, in cyan Liao https://orcid.org/0000-0002-7198-2182, Sydney E. Parks, Kiran L. Sharma https://orcid.org/0000-0002-1988-389X, Kurt M. Drill https://orcid.org/0000-0002-3183-4118, Qiuji Ye https://orcid.org/0000-0002-3812-3001, Feng Li https://orcid.org/0000-0002-9680-4614, Murugesan Palaniappan https://orcid.org/0000-0003-4916-6565, Zhi Tan, Fei Yuan, Chad J. Creighton, A dog Tang, Ramya P. massaging, Xiaoming Guan, Damian W. Younger, Diana Monsivais [email protected]and Martin M. Matzuk https://orcid.org/0000-0002-1445-8632 [email protected]Authors Files […]

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Identification of clinically connected T cell receptors for personalized T cell remedy the usage of combinatorial algorithms

Identification of clinically connected T cell receptors for personalized T cell remedy the usage of combinatorial algorithms

Technology tamfitronics Major Adoptive cell switch (ACT) of tumor-infiltrating lymphocytes (TILs) is a personalised immunotherapy potential with demonstrated superiority over second-line checkpoint blockade immunotherapy in patients with melanoma1,2. Recent be taught show that the frequency of tumor-reactive T cells (TRTs) in melanoma tumors ancient to amplify TILs, and their quantity in cognate TIL merchandise infused […]

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