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Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein

Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein

Technology tamfitronics Main Clustered regularly interspaced short palindromic repeats (CRISPR)–Cas9-based genome editing1,2,3 has the potential to provide wide-ranging treatments for genetic diseases4,5,6 if safe and effective methods for delivering CRISPR-based therapeutics can be developed7,8. Although viral delivery of CRISPR genome editors is the most widely used method for in vivo cell editing9,10,11, viral vectors can […]

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