CRISPR screens of tumor-infiltrating NK cells identify genetic checkpoints for CAR-NK therapy
Technology tamfitronics Research Briefing Published: 25 June 2024 Nature Biotechnology (2024)Cite this article Subjects We use a CRISPR screening platform based on adeno-associated virus and the Sleeping Beauty transposon (AAV-SB-CRISPR) to perform in vivo CRISPR screens in primary natural killer (NK) cells across four different tumor models, and identify calcium homeostasis modulator family member 2 […]