Targeting double-stranded nucleic acids using the λExo–pDNA system
Technology tamfitronics Research Briefing Published: 18 September 2024 Nature Biotechnology (2024)Cite this article Subjects λ exonuclease (λExo) binds 5′-phosphorylated single-stranded DNA (pDNA) at complementary regions on double-stranded DNA and DNA–RNA duplexes under ambient conditions without a PAM-like motif. In the presence of Mg2+λExo then digests the pDNA into nucleotides. This is a preview of subscription […]
